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Increased Ca 2+ mobilization may be achieved in future novel treatment strategies by co-targeting G q -coupled GPCRs present in beta cells, including FFA1 and 2

Ozempic is primarily used to treat Type 2 diabetes in adults and can help patients manage their blood sugar levels while also reducing the risk of cardiovascular events

doi: 10.1016/j.isci.2021.103382 46 BarnettA

Kidney and cardiovascular outcomes among patients with CKD receiving GLP-1 receptor agonists: a systematic review and meta-analysis of randomized trials

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In the results of a cohort study published in BMJ, new users of GLP-1 receptor agonists had a 30% lower risk of severe COPD exacerbation compared to new sulfonylurea users