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doi: 10.1038/s41467-018-03421-7

H.KangJ

Importantly, considering the preclinical evidence indicating that these compounds might hinder bone formation by engaging with YR2 within the hypothalamus, it becomes imperative to investigate the impact of PYY analogs on human osteoblasts both in vitro and in vivo

10.2337/dc12-2006

Because these medications reduce overall food intake, the quality of every calorie consumed becomes more important

However, the studies were relatively small, and longer-term confirmation is still needed