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Any deviation from licensed dosing regimens should only occur under close medical supervision, as the risk-benefit profile at sub-therapeutic doses remains poorly characterised and may not provide the intended clinical outcomes

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Moreover, the degree of brain activation in response to food cues has also been associated with the relative degree of satiety or nausea in individuals receiving GLP-1RAs [78]

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The combined effects of probiotics and restricted calorie diet on the anthropometric indices, eating behavior, and hormone levels of obese women with food addiction: a randomized clinical trial