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Pros Cons May increase the risk of suicidal thoughts Can interact with many other medications May cause nausea, constipation, headache, vomiting, and insomnia Contrave side effects The side effects associated with taking Contrave are typically mild
For adults looking beyond generic formulas, a metabolic support probiotic is usually discussed in the context of gut barrier health, microbial signaling, and long-term metabolic balance rather than short-term symptom relief

A structured medical weight loss program should begin with a physician evaluation and include ongoing physician oversight

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However, recent large cohort studies have not supported an increased risk of suicidality compared to other diabetes medications
The Pharmaceutical Benefits Advisory Committee (PBAC) Guidelines