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Prescription: We weigh the pros and cons of Semaglutide vs

Proper hydration supports muscle function, reducing the risk of cramps and fatigue during physical activity

Although the magnitude of increase from week 68 to week 120 was greater in the semaglutide arm than in the placebo arm (Table S1), the semaglutide arm maintained a small relative improvement versus the placebo arm in HbA1c at week 120 (Figure 2)

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4 Challenges and future directions 4.1 Safety considerations The safety profile of dual or triple receptor agonists targeting GLP-1, GIP, and GCG receptors in the treatment of MASLD and related metabolic disorders warrants careful evaluation

Clinical trials have shown that Semaglutide can lead to substantial weight loss when combined with lifestyle interventions