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While the researchers found no significant differences were found in the parameters over a 12-month period, their results also showed a trend of BMI reduction and possible acetazolamide dose reduction following GLP-1 initiation

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GLP-1RAs disrupt this inflammatory cascade by diminishing adipose tissue macrophage infiltration, enhancing insulin sensitivity via reduced inflammatory signaling, and safeguarding pancreatic -cells from inflammatory harm (Pang et al
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Glucagon-like peptide-1 receptor agonist use in patients with psoriasis is associated with lower incidence of atherosclerotic cardiovascular disease: a retrospective cohort study using trinetx

GLP-1RAs were initially developed as agents to control blood glucose in individuals with diabetes, but CVOTs over the last decade have established these medications as a cornerstone for the reduction of CV events in high-risk populations
