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Other oral compounds like CT-996 / RG 6652 showed a clinically meaningful weight reduction of 6-7% in four weeks among participants without T2D, and GSBR-1290 has demonstrated favourable safety, tolerability and efficacy results

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Finally, we presented our insights on clinical concerns such as appropriate trial endpoints, management of comorbidities, and future developments

Although glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have demonstrated cardiovascular and kidney benefits in the general population with type 2 diabetes mellitus (T2DM), evidence regarding their effects in diabetic KTRs is limited

GLP-1 drugs like semaglutide may reduce opioid addiction cravings and overdose risk, according to new research.