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Fatigue is a recognised side effect when starting glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), or liraglutide (Victoza, Saxenda)

Interestingly, some studies suggest that GLP-1 receptor activation also affects the nervous system

SN : How might these drugs work to prevent cancer

As of 2024, only about half of private employer-sponsored plans in the U.S

[DOI] [PMC free article] [PubMed] [Google Scholar] 41.Chapman M.B., Norwood D.A., Price C., et al

After 36 weeks, the placebo group had lost an average of 2.3%, or 5.3 pounds, compared to 9.4% to 14.7%, or 21.6 to 34 pounds, in the orforglipron groups