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Gitanjali Srivastava, Vanderbilt Medical Center Table of Contents Part 1: Advantages of GLP-1RAs for Addiction Part 2: Research Evidence Part 3: Towards Broad Adoption Introduction Evidence that GLP-1 treatments like Ozempic and Mounjaro have strong anti-addictive effects across substances and behaviors has been mounting every month

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The Peterson-KFF Health System Tracker reports that the list price for Wegovy in the United States is approximately $1,349 per month, while Ozempic costs approximately $936 monthly before insurance adjustments

This combination of preference toward GIP receptor and distinct signaling properties at GLP-1 suggest this biased agonism increases insulin secretion

doi: 10.2337/db06-0006

doi: 10.1016/j.cell.2016.05.023