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Patients should also seek medical review if diarrhoea significantly impacts quality of life or daily functioning, even if not medically severe

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By targeting both pathways at once, Tirzepatide produces a more comprehensive metabolic effect than GLP-1 alone

Although the precise mechanism of its renoprotective effect is unclear, recent studies have suggested that it may involve glycemic control, weight loss, and improvements in blood pressure and lipid profiles

Early studies and FDA warnings raised questions about possible links between GLP-1 medications and certain types of cancer