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Clinical Significance: These data suggest that orforglipron could provide an oral alternative to injectable GLP-1 therapies

they have recently pivoted away from most compounded GLP-1s to partner directly for brand-names like Zepbound and Wegovy, which are often prohibitively expensive without insurance coverage

For T2D and maybe other diseases as well, GLP-1's pleiotropic characteristics make it an attractive treatment option [38]

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