fda compounding semaglutide crackdown november 2025 to Restrict Ingredients Used in Mass-Marketed Compounded GLP-1s, Crack Down on Misleading Ads The FDA announced plans to

Schlachetzki JCM: chronic peripheral inflammation: a possible contributor to neurodegenerative diseases

Chen, Q., Shou, P., Zheng, C., Jiang, M., Cao, G., Yang, Q., Cao, J., Xie, N., Velletri, T., Zhang, X., Xu, C., Zhang, L., Yang, H., Hou, J., Wang, Y., & Shi, Y

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Semaglutide does activate GLP-1 receptors in brain regions that regulate mood and stress response, making direct causation plausible in some patients

doi: 10.1016/j.mce.2013.11.010 33 JonesBBuenaventuraTKandaNChabosseauPOwenBMScottRet al

The conversation also raises bigger questions about transparency in clinical trials, what drug companies knew about these anti-hedonic effects, and why something so impactful may not have been formally tracked