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Abbreviations ACE angiotensinconverting enzyme ARB angiotensin receptor blocker ASCVD atherosclerotic cardiovascular disease BP blood pressure CKD chronic kidney disease CMR cardiac magnetic resonance CRP Creactive protein CV cardiovascular DBP diastolic blood pressure EF ejection fraction eGFR estimated glomerular filtration rate FMD flowmediated dilation GIP glucosedependent insulinotropic polypeptide GLP1 glucagonlike peptide1 GLP1RA GLP1 receptor agonist HbA1c haemoglobin A1c HF heart failure HFmrEF heart failure with mildly reduced ejection fraction HFpEF heart failure with preserved ejection fraction HFrEF heart failure with reduced ejection fraction IL6 interleukin6 LV left ventricle/left ventricular LVEF left ventricular ejection fraction MACE major adverse cardiovascular events NTproBNP Nterminal proBtype natriuretic peptide NYHA New York Heart Association PGIS patient global impression of severity PWV pulsewave velocity SBP systolic blood pressure SGLT2 sodiumglucose cotransporter 2 T2DM type 2 diabetes mellitus 1