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Early in the week : Some people prefer Monday or Tuesday so that side effects resolve well before weekend plans

Lifestyle interventions including structured dietary programmes, increased physical activity, and behavioural support remain the cornerstone of sustainable weight management and should underpin any pharmacological approach

According to the drugs prescribing information, about 11% of adults in clinical trials reported fatigue as a side effect, compared to 5% in the placebo group

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It is not a medicinal product, is not for human or veterinary consumption, and is not intended to diagnose, treat, cure or prevent any disease

The efficacy tradeoffs with semaglutide split dosing are smaller because there is no glucagon threshold concern
