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[DOI] [PubMed] [Google Scholar] 354.Sellam, J
57 UPR is mainly involved in the activation of three transmembrane proteins, inositol-requiring enzyme 1 (IRE-1), activating transcription factor 6 (ATF6), and protein kinase R (PKR)-like ER kinase (PERK)
European Neuropsychopharmacology
Biochem Pharmacol (2017) 132:11832
2025;26(7):e13916
Their peptide structure closely mimics the natural GLP-1 hormone, giving them high receptor binding affinity and predictable pharmacokinetics
