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Eli Lilly and Company recommends storing Mounjaro vials or pens in a refrigerator at a temperature range between 36F and 46F (2C 8C)

On the cardiovascular side, the SUSTAIN-6 trial in 2016 was one of the first to report a significant reduction in major adverse cardiovascular events with semaglutide in adults with type 2 diabetes and high cardiovascular risk (Marso et al., NEJM, 2016)

That is the active ingredient in Wegovy and its diabetes counterpart Ozempic, Novo Nordisk's two GLP-1s that are still on the FDA's drug shortage list

Ozempic and Surgery: When to stop and restart

Zepbound is specifically indicated as an adjunct to a reduced-calorie diet and increased physical activity

But the transition from higher baseline glucose levels to lower, more regulated levels is not always smooth