companies making glp-1 drugs glp 1 3 Companies at the Forefront of the Pill Wars Gaining An Edge In GLP-1
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It should never be used in patients with coronary artery disease, arrhythmias, uncontrolled hypertension, or a history of drug abuse

It is important to note that semaglutide is fundamentally different from SGLT-2 inhibitors like empagliflozin or dapagliflozin, which work by increasing glucose excretion through urine

T2DM: Type 2 diabetes mellitus

Both, SGLT2 inhibitors and GLP1 receptor agonists, had similar effect on MACE reduction, but SGLT2 inhibitors have far more benefits in patients with heart failure

13 Two meta-analyses of other GLP-1 RA CVOTs found that GLP-1 RAs were associated with greater rates of DR progression, but both studies found that the effect was driven by the extent of hemoglobin A1c reduction, rather than the medications themselves
