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As science continues to uncover how GLP-1 receptor agonists interact with the brains reward circuits, new possibilities are emerging

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Individual genetics, lifestyle factors, and medication type all influence weight loss outcomes

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that acts on the same receptor as the endogenous incretin hormone which works by selectively binding and activating the GLP-1 receptor to increase glucose-dependent insulin secretion, reducing appetite, and slows gastric emptying

Adults aged18 years with diabetes prescribed biguanides were included