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On Monday, the United Nations health agency issued its first guidelines on how such drugs could be used as a key tool for treating obesity in adults as a chronic, relapsing disease

If youre concerned about digestive side effects or have a history of gastrointestinal issues, discuss these with your doctor before starting treatment

Potcovaru CG, Filip PV, Neagu OM, Diaconu LS, Salmen T, Cintez D, et al

Mechanistically, the stabilization objective is to prevent progression toward a redox bottleneck , in which oxidative throughput approaches the regenerative capacity of NAD/NADPH-dependent buffering systems

Theyre fascinating drugs for which scientists have already found many good uses, Standaert says, but that doesnt mean they cure everything. At this point, he says, I think we need to back up a little bit and ask ourselves, How do these GLP-1s work anyway? Sperling echoes the thought

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