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Description
Although the name can be a bit misleading, Glucagon-Like Peptide-1 agonists (GLP-1s) are diabetes drugs that mimic the natural gut hormone GLP-1, which, unlike glucagon, decreases your blood sugar and reduces glucagon, especially after meals

This occurs because GLP-1 receptor activation reduces the coordinated muscular contractions (peristalsis) that normally propel stomach contents into the small intestine

Curr Top Microbiol Immunol (2017) 410:99126

A 753-P: Tirzepatide improves HRQoL compared with insulin lispro in poorly controlled basal insulin-treated adults with long-standing T2D (SURPASS-6)

The efficacy and safety of the combination therapy with GLP-1 receptor agonists and SGLT-2 inhibitors in type 2 diabetes mellitus: a systematic review and meta-analysis

Yabe, Kuwata, Seino)