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Avoiding high-fat and spicy foods is essential: fatty meals slow gastric emptying further, while capsaicin in hot peppers irritates an already-sensitive esophageal lining

The findings, which were presented over the weekend at ENDO 2026, the Endocrine Society's annual meeting, were based on an analysis of health records from more than 42,000 adults who were already taking at least two types of blood pressure medications when they began treatment with GLP-1 drugs such as semaglutide, tirzepatide or liraglutide

however, their clinical application remains investigational [133]

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This, combined with reduced stomach capacity and altered appetite signaling in your brain, causes alcohol to produce stronger intoxicating effects at lower doses than you experienced before therapy

10.3390/ph15060740 [DOI] [PMC free article] [PubMed] 7.Gilbert MP, Pratley RE (2020) GLP-1 analogs and DPP-4 inhibitors in type 2 diabetes therapy: review of Head-to-head clinical trials