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N Engl J Med 377(3):300301

& Islam, R

GLP-1 receptor agonists reduce CGRP expression, lower neuroinflammation, and decrease intracranial pressure, all of which are relevant to migraine pathophysiology

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GLP-1 has multifaceted actions, including glucose-induced stimulation of insulin biosynthesis and secretion, inhibition of glucagon secretion, regulation of gene expression, trophic effects on cells, inhibition of food intake, and slowing of gastric emptying
