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current evidence indicates that GLP-1 R expression is found predominantly within the ganglion cell layer (GCL), exclusively detected in a discrete subpopulation of neurons [37]

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Harvard Health's coverage of the same review noted that anemia due to nutritional deficiency affected 4% of the study population within a year, on top of the vitamin D findings (Harvard Health, 2026)

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With the creation of more potent GLP-1RA, the weight-reducing effects were enhanced to a point where they were considered for treatment of people with obesity without diabetes 2