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Were also hopeful that increased competition and Medicare drug price negotiations will help bring prices down. Semaglutide is already among the first 15 drugs selected for Medicare price negotiations under the Inflation Reduction Act, with changes expected to take effect in 2027

Nagashima M, Watanabe T, Terasaki M, Tomoyasu M, Nohtomi K, Kim-Kaneyama J, Miyazaki A, Hirano T: Native incretins prevent the development of atherosclerotic lesions in apolipoprotein E knockout mice

doi:10.3389/fphar.2022.925377 Bezin J, Gouverneur A, Pnichon M, Mathieu C, Garrel R, Hillaire-Buys D, et al

Limit greasy, heavy, or spicy foods

Actual cost-sharing varies by plan, but beneficiaries can expect meaningful copays or coinsurance until they reach their out-of-pocket threshold

This appears to be consistent with the observations made for exendin-4 under the same circumstances