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Weeks 3-4: Appetite Shifts Begin Week three marks the first noticeable change for most users

[DOI] [PubMed] [Google Scholar] [53].Rosenstock J, Raccah D, Koranyi L, Maffei L, Boka G, Miossec P, Gerich JE, Efficacy and safety of lixisenatide once daily versus exenatide twice daily in type 2 diabetes inadequately controlled on metformin: a 24-week, randomized, open-label, active-controlled study (GetGoal-X), Diabetes care, 36 (2013) 29452951

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As a result, recent international guidelines emphasize the pivotal role of GLP-1 receptor agonists, particularly for individuals with atherosclerotic cardiovascular disease or obesity