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Description
However, simply showing that the enzyme can cleave a substrate in vitro does not necessarily mean that DPP-4 plays an important physiological role in regulating concentrations and/or modulating biological activity of the endogenous molecules, particularly in humans and, for many of these putative substrates, there is little, if any experimental evidence to show that DPP-4 does actually cleave them in vivo and/or whether this has any physiological consequence
Limit Refined Sugars and Carbs Highly processed foods that spike blood sugar can undermine GLP-1's natural role
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Liraglutide 2000 , FDA 2010
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