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While lower prices improve access, ensuring quality, pharmacovigilance and appropriate use will be key to maximising public health benefits
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Understanding these benefits and risks is essential for those considering semaglutide as part of their health journey
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or for patients with diabetes and at high risk of liver fibrosis, as there are potential beneficial effects on MASLD.(4) Studies of GLP-1 RA Use in Patients with Cirrhosis A retrospective study in Taiwan, using matched pairs in which half of the patients used GLP-1 RAs, and the other half did not, included patients with type 2 diabetes and compensated cirrhosis
The GIP component already provides some receptor tolerance overlap, but the glucagon agonism is entirely new territory
