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What the 2025 Gastroenterology Metaanalysis Found The systematic review and metaanalysis (DOI: 10.1053/j.gastro.2025.06.003) evaluated safety outcomes across randomized trials and realworld studies of GLP1 RAs
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2021: semaglutide 2.4 mg led to substantial fat mass reduction, while lean mass also declined in absolute terms, but the of lean mass relative to total body mass actually increased
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