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The combination of ATP elevation with complex I super-activation suggests that mitochondria were under a stress response in the DIO mice

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Most diarrhea episodes resolve within 24-48 hours during the adjustment period

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Action of glucagon-like peptide 1 and glucose levels on corticotropin-releasing factor and vasopressin gene expression in rat hypothalamic 4B cells

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Saller CF, Stricker EM

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And the answer is more nuanced than a simple yes or no

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Evidence also points to potential effects on emotional well-being, including reduced libido and feelings of detachment or emotional flatness in relationships

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