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Avoid excessively restrictive eating patterns that may compound nutritional deficits

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Among a small subgroup of participants who smoked cigarettes at baseline, those treated with semaglutide had significantly greater reductions in average cigarettes per day compared to those in the placebo group, suggesting that semaglutide might reduce both alcohol and nicotine use

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Many patients find this gentler curve makes the transition to long-term therapy psychologically easier, as the early experience feels manageable rather than disruptive