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The anatomical preparation contains the sinus node, confirmed by positive hyperpolarization-activated cyclic nucleotidegated channel 4 (HCN4) staining, as well as surrounding atrial tissue (see Supplementary material online, Figure S7 )

, & Menzies, J

Klinitzke G, Steinig J, Blher M, Kersting A, Wagner B (2013) Obesity and suicide risk in adultsa systematic review

Gradual estrogen decline: As ovarian reserve decreases, estrogen trends lower overall (though it can still spike unpredictably earlier in perimenopause)
