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When coupled to -arrestins, GPCRs are desensitized by abrogated coupling to G proteins and trafficked away from the cell surface, destined for either re-sensitization following their recycling back to the plasma membrane, or for final signal termination resulting from their degradation in lysosomes (McCorvy et al., 2017)

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Ozanta 0.25mg/0.5mg Injection is administered as a once-weekly injection

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It also has been approved for the treatment of obesity in children ages 12 and older

doi: 10.1093/ibd/izae250 102 St-PierreJKleinJChoiNKFearEPannainSRubinDT