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Cardiovascular outcome trials (CVOTs) in people living with type 2 diabetes mellitus and obesity have confirmed the cardiovascular benefits of glucagon-like peptide 1 receptor agonists (GLP-1RAs), including reduced cardiovascular mortality, lower ...

Retatrutide is a novel synthetic peptide designed as a triple agonist, targeting GLP-1, GIP, and glucagon receptors

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GLP-1 users who carry an active Ozempic, Wegovy, Mounjaro, or Zepbound pen alongside a backup or transition pen

The botanical product kratom produces opioid-like effects at high doses and is sometimes used for opioid replacement by individuals with opioid use disorder