can glp 1 cause vomiting and diarrhea GLP-1: The Diabetes Drug Changing How We Think About Weight Loss Full article: Managing the gastrointestinal

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For some people who are particularly vulnerable to sarcopenia, it is important to be cautious when using GLP-1s to avoid too much loss of muscle mass

GLP-1 acts through a class 2 member of the G-coupled protein C receptor family seven-transmembrane receptor (GLP-1R) (8), which is mainly expressed in pancreatic islets, the brain, and the gastrointestinal (GI) tract (912), and less prominently in the kidney and eyes (1113)

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Neurogastroenterol Motil 25(1):e60e69

Each time a new gut peptide was identified, scientists tested its effect on insulin secretion, but only one intestinal hormone, GIP (glucose-dependent insulinotropic polypeptide), satisfied these criteria