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The timeline for weight loss effects reflects this, with meaningful appetite changes emerging at 4 to 8 weeks of escalating doses

Diabetes Care (2013) 36(9):254350

Amylin dose-dependently suppresses arginine-mediated glucagon secretion in rats [597] whereas pharmacological inhibition of amylin signaling enhances glucagon secretion [598]

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The most common side effects of either drug are usually mild