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While GLP-1 agonists have been on the market for a few years now, longitudinal studies are needed on large groups of individuals for any conclusive findings

Combination drugs Medications like Qsymia and Contrave are more likely to be on formularies since theyre older and less expensive than GLP-1s

GLP-1 has also been found to increase mRNA and protein expression levels of AP2 and PPAR in a dose-dependent manner during pre-3T3-L1 adipocyte differentiation
Intensified multifactorial intervention in type 2 diabetics with microalbuminuria leads to long-term renal benefits
Barroso B, Gmez-Lpez A, Valverde-Monge M, et al

10.1517/14712598.2015.1000329 57 TanT