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The results were encouraging - those on the 0.5 mg dose experienced an average weight loss of 7.6 kg (16.8 pounds) in three months and 11.5 kg (25.4 pounds) over six months

JAMA 2007;298:2038e47

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Heart Rate Increase: Both adults and pediatric patients experienced mean increases in resting heart rate of 1 to 4 beats per minute (bpm) in semaglutide patients compared to placebo in clinical trials

Considering injectable options such as Zepbound for its dual-action benefits

38 Phase 3 trials in people with obesity (REDEFINE-1) or people with obesity plus T2D (REDEFINE-2), CagriSema achieved 20.4 per cent and 13.7 per cent weight loss respectively