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doi: 10.1515/BC.2008.019
According to the group of authors, these polyagonists are in all likelihood the next step towards a cure for diabetes and obesity. Comparable to bariatric surgery The authors report on various polyagonists that are currently being researched in clinical studies and show improved efficacy with each new generation. The latest triple agonists attack both the glucose-dependent insulinotropic peptide receptor (GIPR) and the receptors for glucagon-like peptide 1 (GLP1) and glucagon (GCG, a hormone from the pancreas)
These effects could be attributed to treatment with liraglutide and not to weight loss, since they were not observed in the group of animals that lost weight without receiving the GLP-1RA [40]

The medications can also help quiet food noise, or constant thoughts about food
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thyroid cancer or hyperthyroidism, gastroparesis, pancreatic cancer or pancreatitis, MEN2 syndrome, or inflammatory bowel disease)

2021;29(7):679693e6
