health biotech news today obesity drugs glp-1 CVS drug deal puts Lilly on equal footing with Novo Why GLP-1 drugs are changing

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One preclinical study compared the effects of single GIPR or GLP-1R agonism and combined GLP-1R/GIPR agonism in female APOE*3-Leiden.CETP mice fed a Western-type diet, a well-established mouse model for human-like lipoprotein metabolism and atherosclerotic development, for 10 weeks

Ongoing studies in the STEP program will provide further insights into the effects of once-weekly semaglutide 2.4 mg in a broader population [22]

Combining a GLP-1 agonist and a DPP-4 inhibitor for type 2 diabetes

The Wegovy pill costs $149 a month for a 1.5 mg dose, but can go as low as $25 per month if covered by insurance

Preclinical work also points to applications in reproductive health (e.g., PCOS-related fertility improvements) and oncology, where observational studies link GLP-1 use to lower risks of obesity-related cancers