ascendis pharma glp-1 receptor agonists weight management diabetes treatments agonist medications Frontiers ascendis pharma glp-1 receptor agonist
Description
As an example, the Amgen drug MariTide is showing impressive results in trials
reported greater weight loss in obese mice with the GLP-1/GIP/glucagon receptor triagonist compared to GLP-1 receptor agonists, GIP/GLP-1 receptor co-agonists and GLP-1/glucagon receptor agonists including semaglutide and tirzepatide [60]
The mechanism parallels the early worsening seen in the DCCT and UKPDS studies after intensive glucose reduction
For these reasons, limited treatment options exist for this patient population
V., Clarke G., Dinan T
New England Journal of Medicine, 375 ,
