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Adults do maintain brown fat deposits, primarily in the supraclavicular region (above the collarbones), along the spine, and around major blood vessels

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This is the chart you will reference week after week as you titrate upward

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However, recent evidence suggests that non-12-OH FXR-antagonistic BAs in humans exert similar metabolic effects observed for those non-12-OH FXR-antagonistic BAs in rodents 29