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The mechanism of action is attributed to the GIP/GLP-1 receptor co-agonism being enhanced by glucagon receptor activation and augmentation of energy intake, substrate utilisation and energy expenditure [60]

1, they continue to cover the drugs for other health issues, such as Type 2 diabetes, cardiovascular disease and chronic kidney disease

doi: 10.1523/JNEUROSCI.2170-16.2016 123 HuangJLiuYChengLLiJZhangTZhaoGet al

It was noted as being the first FDA-approved type 2 diabetes medication to reduce major adverse cardiovascular events (MACE) in adults

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That's why they need an empty stomach and a 30-minute fast afterward