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The purpose of this review is to summarise the physiological effects as well as the therapeutic implications of the gut hormones glucagon-like peptide-1 (GLP-1), oxyntomodulin, peptide YY (PYY), and glucose-dependent insulinotropic peptide (GIP) in the treatment of obesity and type 2 diabetes

Earlier use of pharmacotherapy is encouraged Medications should be considered early, especially in patients withor at high risk ofobesity-related complications

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2026 updates to cgm, glp-1 ra, sglti, diabetes coverage in Michigan, with the new 2026 PDF MCT2D coverage guide and guidelines that have changed

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