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Its the reason the FDA has been hesitant to approve GLP-1 use for people with type 1 diabetes, says Dace Trence, MD, the president of American Association of Clinical Endocrinology and a professor emeritus at the University of Washington in Seattle

Wegovy is titrated up to 2.4 mg weekly, while diabetes formulations like Ozempic and Rybelsus use lower ranges

CNS receptor occupancy research Studying the central effects of GLP-1 receptor agonists requires brain delivery

So even if you are on the GLP 1 and Ive talked to many of these people, theyre not losing the amount of weight they want to lose because they have other barriers to eating the way or exercising the way theyd like to

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