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One of the most surprising things people report when starting or adjusting a GLP-1 medication is feeling more hungry, not less.

The results suggest that highly effective diabetes treatments may soon become available in a much more convenient pill form.

Enter novel therapeutics like CCT217: By driving beige fat activation and functional thermogenesis, these agents could rapidly improve insulin sensitivity, ApoB/TG, hsCRP, hepatic fat, and microvascular functioneven before the scale moves

A new review from the Schmidt lab at Penn pulls the preclinical and emerging clinical evidence together

Insulin pathways in epilepsy: Link between metabolism and brain activity
