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The gut and beyond: GI effects and other tissues In the gastrointestinal tract, the receptor appears in the Brunners glands of the duodenum, in parietal cells, and in gastric smooth muscle, where it slows gastric emptying

In addition to GLP-1RAs, pioglitazone and SGLT-2 inhibitors are two other classes of diabetic medications that have shown promise in reducing the risk of cardiovascular disease, albeit through different mechanisms

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