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a 31-year-old female patient with obesity, a history of smoking, and a HS-Physicians Global Assessment (HS-PGA) of 4, indicative of severe disease

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GLP-1RAs enhance central serotonin signaling, while selective serotonin reuptake inhibitors increase serotonin availability, potentially amplifying GLP-1mediated effects
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In clinical studies for Janumet, researchers did not actually use Janumet
