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Pharmacologic therapy should be guided by person-centered treatment factors, including comorbidities, considerations of adverse effects (including hypoglycemia), treatment burden, and treatment goals and preferences

The effect isn't instant, and it's not a substitute for adequate protein or sunscreen, but it can be a useful layer of support

To view or add a comment, sign in New research in Cardiovascular Diabetology A new open-access study with CTCPR - Center for Translational Cardiology and Pragmatic Randomized Trials and international collaborators explores subclinical cardiac dysfunction in people with type 2 diabetes without overt cardiovascular disease

Oral semaglutide begins at $249 per month for patients who prefer tablet administration, though injection therapy typically provides more consistent appetite suppression due to higher bioavailability

In light of this, GLP-1 RAs provide a high potential of being incorporated into diabetic patients' treatment plans, similar to SGLT-2 inhibitors, as they decrease MACE by 14%, macroalbuminuria by 26%, and the risk of all-cause mortality by 12% [15,49]

Promising pipeline GLP agonists such as XW014, Survodutide, MK-6024, ECC5004, RGT001-075, Tirzepatide, CT 388, Pegylated exenatide, VK2735, MLX 7000 and others are under different phases of GLP agonist clinical trials