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The Epac2 arm activates PLC epsilon through Rap1 and this also leads to increased intracellular Ca 2+ ( Figure 3 )

Allergic Reactions Any signs of an allergic reaction, for instance, difficulty breathing, inability to swallow, or red covering the face, should seek medical help immediately

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Mild weight fluctuations : Some people may notice small changes in their weight, but significant weight loss usually comes later

After withdrawal from heroin dependent mice, significant withdrawal symptoms appear

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