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By promoting weight loss and reducing inflammatory markers, tirzepatide may create conditions that allow for a gradual corticosteroid taper
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These findings indicate that GLP-1R activation specifically inhibits GSDMD-mediated microglial pyroptosis, a finding consistently replicated in subsequent in vitro experiments (Song et al., 2022)

Available at: (Accessed August 10, 2022)
The board earlier this month tabled a vote on all the proposed changes

Beavers KM, Neiberg RH, Johnson KC, Davis CH, Casanova R, Schwartz AV, et al